A high-affinity cocaine binding site associated with the brain acid soluble protein 1

Cocaine exerts its stimulant effect by inhibiting dopamine (DA) reuptake, leading to increased dopamine signaling. This action is thought to reflect the binding of cocaine to the dopamine transporter (DAT) to inhibit its function. However, cocaine is a relatively weak inhibitor of DAT, and many DAT...

Descripción completa

Detalles Bibliográficos
Autores principales: Harraz, Maged M., Malla, Adarsha P., Semenza, Evan R., Shishikura, Maria, Singh, Manisha, Hwang, Yun, Kang, In Guk, Song, Young Jun, Snowman, Adele M., Cortés, Pedro, Karuppagounder, Senthilkumar S., Dawson, Ted M., Dawson, Valina L., Snyder, Solomon H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9169839/
https://www.ncbi.nlm.nih.gov/pubmed/35412917
http://dx.doi.org/10.1073/pnas.2200545119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9169839/
https://www.ncbi.nlm.nih.gov/pubmed/35412917
http://dx.doi.org/10.1073/pnas.2200545119

Ejemplares similares