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Structural insights into sphingosine-1-phosphate receptor activation

As a critical sphingolipid metabolite, sphingosine-1-phosphate (S1P) plays an essential role in immune and vascular systems. There are five S1P receptors, designated as S1PR1 to S1PR5, encoded in the human genome, and their activities are governed by endogenous S1P, lipid-like S1P mimics, or nonlipi...

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Detalles Bibliográficos
Autores principales: Yu, Leiye, He, Licong, Gan, Bing, Ti, Rujuan, Xiao, Qingjie, Yang, Xin, Hu, Hongli, Zhu, Lizhe, Wang, Sheng, Ren, Ruobing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9169846/
https://www.ncbi.nlm.nih.gov/pubmed/35412894
http://dx.doi.org/10.1073/pnas.2117716119