A hypothalamic pathway for Augmentor α–controlled body weight regulation

Augmentor α and β (Augα and Augβ) are newly discovered ligands of the receptor tyrosine kinases Alk and Ltk. Augα functions as a dimeric ligand that binds with high affinity and specificity to Alk and Ltk. However, a monomeric Augα fragment and monomeric Augβ also bind to Alk and potently stimulate...

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Detalles Bibliográficos
Autores principales: Ahmed, Mansoor, Kaur, Navjot, Cheng, Qianni, Shanabrough, Marya, Tretiakov, Evgenii O., Harkany, Tibor, Horvath, Tamas L., Schlessinger, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9169862/
https://www.ncbi.nlm.nih.gov/pubmed/35412887
http://dx.doi.org/10.1073/pnas.2200476119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9169862/
https://www.ncbi.nlm.nih.gov/pubmed/35412887
http://dx.doi.org/10.1073/pnas.2200476119

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