A Novel STAT3 Gain-of-Function Mutation in Fatal Infancy-Onset Interstitial Lung Disease

Signal transducer and activator of transcription 3 (STAT3) gain-of-function (GOF) mutations cause early-onset immune dysregulation syndrome, characterized by multi-organ autoimmunity and lymphoproliferation. Of them, interstitial lung disease (ILD) usually develops after the involvement of other org...

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Detalles Bibliográficos
Autores principales: Deng, Mengyue, Li, Yue, Li, Yulu, Mao, Xiaolan, Ke, Han, Liang, Weiling, Lei, Xiaoguang, Lau, Yu-Lung, Mao, Huawei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9169891/
https://www.ncbi.nlm.nih.gov/pubmed/35677041
http://dx.doi.org/10.3389/fimmu.2022.866638

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9169891/
https://www.ncbi.nlm.nih.gov/pubmed/35677041
http://dx.doi.org/10.3389/fimmu.2022.866638

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