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Extracellular vesicles from triple negative breast cancer promote pro-inflammatory macrophages associated with better clinical outcome

Tumor associated macrophages (TAMs), which differentiate from circulating monocytes, are pervasive across human cancers and comprise heterogeneous populations. The contribution of tumor-derived signals to TAM heterogeneity is not well understood. In particular, tumors release both soluble factors an...

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Detalles Bibliográficos
Autores principales: Tkach, Mercedes, Thalmensi, Jessie, Timperi, Eleonora, Gueguen, Paul, Névo, Nathalie, Grisard, Eleonora, Sirven, Philemon, Cocozza, Federico, Gouronnec, Alizée, Martin-Jaular, Lorena, Jouve, Mabel, Delisle, Fabien, Manel, Nicolas, Rookhuizen, Derek C., Guerin, Coralie L., Soumelis, Vassili, Romano, Emanuela, Segura, Elodie, Théry, Clotilde
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9169908/
https://www.ncbi.nlm.nih.gov/pubmed/35439048
http://dx.doi.org/10.1073/pnas.2107394119