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Freeze-thaw cycles enable a prebiotically plausible and continuous pathway from nucleotide activation to nonenzymatic RNA copying

Nonenzymatic template-directed RNA copying using chemically activated nucleotides is thought to have played a key role in the emergence of genetic information on the early Earth. A longstanding question concerns the number and nature of different environments that might have been necessary to enable...

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Detalles Bibliográficos
Autores principales: Zhang, Stephanie J., Duzdevich, Daniel, Ding, Dian, Szostak, Jack W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9169909/
https://www.ncbi.nlm.nih.gov/pubmed/35446612
http://dx.doi.org/10.1073/pnas.2116429119