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Freeze-thaw cycles enable a prebiotically plausible and continuous pathway from nucleotide activation to nonenzymatic RNA copying
Nonenzymatic template-directed RNA copying using chemically activated nucleotides is thought to have played a key role in the emergence of genetic information on the early Earth. A longstanding question concerns the number and nature of different environments that might have been necessary to enable...
Autores principales: | Zhang, Stephanie J., Duzdevich, Daniel, Ding, Dian, Szostak, Jack W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9169909/ https://www.ncbi.nlm.nih.gov/pubmed/35446612 http://dx.doi.org/10.1073/pnas.2116429119 |
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