Structural and functional insight into mismatch extension by human DNA polymerase α

Human DNA polymerase α (Polα) does not possess proofreading ability and plays an important role in genome replication and mutagenesis. Polα extends the RNA primers generated by primase and provides a springboard for loading other replication factors. Here we provide the structural and functional ana...

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Detalles Bibliográficos
Autores principales: Baranovskiy, Andrey G., Babayeva, Nigar D., Lisova, Alisa E., Morstadt, Lucia M., Tahirov, Tahir H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9169922/
https://www.ncbi.nlm.nih.gov/pubmed/35467978
http://dx.doi.org/10.1073/pnas.2111744119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9169922/
https://www.ncbi.nlm.nih.gov/pubmed/35467978
http://dx.doi.org/10.1073/pnas.2111744119

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