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Discovery of unusual dimeric piperazyl cyclopeptides encoded by a Lentzea flaviverrucosa DSM 44664 biosynthetic supercluster

Rare actinomycetes represent an underexploited source of new bioactive compounds. Here, we report the use of a targeted metabologenomic approach to identify piperazyl compounds in the rare actinomycete Lentzea flaviverrucosa DSM 44664. These efforts to identify molecules that incorporate piperazate...

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Detalles Bibliográficos
Autores principales: Li, Chunshun, Hu, Yifei, Wu, Xiaohua, Stumpf, Spencer D., Qi, Yunci, D’Alessandro, John M., Nepal, Keshav K., Sarotti, Ariel M., Cao, Shugeng, Blodgett, Joshua A. V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9169926/
https://www.ncbi.nlm.nih.gov/pubmed/35439047
http://dx.doi.org/10.1073/pnas.2117941119