Early age–related atrophy of cutaneous lymph nodes precipitates an early functional decline in skin immunity in mice with aging

Secondary lymphoid organs (SLOs) (including the spleen and lymph nodes [LNs]) are critical both for the maintenance of naive T (T(N)) lymphocytes and for the initiation and coordination of immune responses. How they age, including the exact timing, extent, physiological relevance, and the nature of...

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Detalles Bibliográficos
Autores principales: Sonar, Sandip Ashok, Uhrlaub, Jennifer L., Coplen, Christopher P., Sempowski, Gregory D., Dudakov, Jarrod A., van den Brink, Marcel R. M., LaFleur, Bonnie J., Jergović, Mladen, Nikolich-Žugich, Janko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9169949/
https://www.ncbi.nlm.nih.gov/pubmed/35439062
http://dx.doi.org/10.1073/pnas.2121028119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9169949/
https://www.ncbi.nlm.nih.gov/pubmed/35439062
http://dx.doi.org/10.1073/pnas.2121028119

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