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Modulation of Inflammation-Related Lipid Mediator Pathways by Celastrol During Human Macrophage Polarization

BACKGROUND AND PURPOSE: Celastrol (CS) is a major active ingredient of the Chinese/Asian herb Tripterygium wilfordii that is frequently used as phytomedicine to treat inflammation and autoimmune diseases. We showed before that short-term exposure to CS (1 µM) favorably impacts the biosynthesis of in...

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Detalles Bibliográficos
Autores principales: Zhang, Kehong, Jordan, Paul Mike, Pace, Simona, Hofstetter, Robert K, Werner, Markus, Chen, Xinchun, Werz, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9169975/
https://www.ncbi.nlm.nih.gov/pubmed/35676971
http://dx.doi.org/10.2147/JIR.S356964