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Long Noncoding RNA MIAT Regulates Hyperosmotic Stress-Induced Corneal Epithelial Cell Injury via Inhibiting the Caspase-1-Dependent Pyroptosis and Apoptosis in Dry Eye Disease

PURPOSE: The biological role and mechanism of long noncoding RNA (lncRNA) myocardial infarction-associated transcript (MIAT) in dry eye remain to be illustrated. Pyroptosis is a noticeable form of inflammatory activation, which is characteristic of gasdermin D (GSDMD)-driven cell death. The present...

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Detalles Bibliográficos
Autores principales: Li, Jinjian, Yang, Kun, Pan, Xinghui, Peng, Hui, Hou, Chenting, Xiao, Jie, Wang, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9169976/
https://www.ncbi.nlm.nih.gov/pubmed/35676970
http://dx.doi.org/10.2147/JIR.S361541