Cargando…

ATR activity controls stem cell quiescence via the cyclin F–SCF complex

A key property of adult stem cells is their ability to persist in a quiescent state for prolonged periods of time. The quiescent state is thought to contribute to stem cell resilience by limiting accumulation of DNA replication–associated mutations. Moreover, cellular stress response factors are tho...

Descripción completa

Detalles Bibliográficos
Autores principales: Salvi, Jayesh S., Kang, Jengmin, Kim, Soochi, Colville, Alex J., de Morrée, Antoine, Billeskov, Tine Borum, Larsen, Mikkel Christian, Kanugovi, Abhijnya, van Velthoven, Cindy T. J., Cimprich, Karlene A., Rando, Thomas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9170012/
https://www.ncbi.nlm.nih.gov/pubmed/35476521
http://dx.doi.org/10.1073/pnas.2115638119