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Phenotypic determinism and stochasticity in antibody repertoires of clonally expanded plasma cells

The capacity of humoral B cell-mediated immunity to effectively respond to and protect against pathogenic infections is largely driven by the presence of a diverse repertoire of polyclonal antibodies in the serum, which are produced by plasma cells (PCs). Recent studies have started to reveal the ba...

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Detalles Bibliográficos
Autores principales: Neumeier, Daniel, Yermanos, Alexander, Agrafiotis, Andreas, Csepregi, Lucia, Chowdhury, Tasnia, Ehling, Roy A., Kuhn, Raphael, Cotet, Tudor-Stefan, Brisset-Di Roberto, Raphaël, Di Tacchio, Mariangela, Antonialli, Renan, Starkie, Dale, Lightwood, Daniel J., Oxenius, Annette, Reddy, Sai T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9170022/
https://www.ncbi.nlm.nih.gov/pubmed/35486691
http://dx.doi.org/10.1073/pnas.2113766119