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Highly motile cells are metabolically responsive to collagen density

Altered tissue mechanics and metabolism have gained significant attention as drivers of tumorigenesis, and mechanoresponsive metabolism has been implicated in migration and metastasis. However, heterogeneity in cell populations makes it difficult to link changes in behavior with metabolism, as indiv...

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Detalles Bibliográficos
Autores principales: Zanotelli, Matthew R., Zhang, Jian, Ortiz, Ismael, Wang, Wenjun, Chada, Neil C., Reinhart-King, Cynthia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9170068/
https://www.ncbi.nlm.nih.gov/pubmed/35471912
http://dx.doi.org/10.1073/pnas.2114672119