Epitope-focused immunogen design based on the ebolavirus glycoprotein HR2-MPER region

The three human pathogenic ebolaviruses: Zaire (EBOV), Bundibugyo (BDBV), and Sudan (SUDV) virus, cause severe disease with high fatality rates. Epitopes of ebolavirus glycoprotein (GP) recognized by antibodies with binding breadth for all three ebolaviruses are of major interest for rational vaccin...

Descripción completa

Detalles Bibliográficos
Autores principales: Schoeder, Clara T., Gilchuk, Pavlo, Sangha, Amandeep K., Ledwitch, Kaitlyn V., Malherbe, Delphine C., Zhang, Xuan, Binshtein, Elad, Williamson, Lauren E., Martina, Cristina E., Dong, Jinhui, Armstrong, Erica, Sutton, Rachel, Nargi, Rachel, Rodriguez, Jessica, Kuzmina, Natalia, Fiala, Brooke, King, Neil P., Bukreyev, Alexander, Crowe, James E., Meiler, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9170092/
https://www.ncbi.nlm.nih.gov/pubmed/35584193
http://dx.doi.org/10.1371/journal.ppat.1010518

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9170092/
https://www.ncbi.nlm.nih.gov/pubmed/35584193
http://dx.doi.org/10.1371/journal.ppat.1010518

Ejemplares similares