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Pre-clinical evaluation of LASSBio-1491: From in vitro pharmacokinetic study to in vivo leishmanicidal activity

Leishmaniasis is a public health issue. It is among the top five parasitic illnesses worldwide and is one of the most neglected diseases. The current treatment disease includes limitations of toxicity, variable efficacy, high costs and inconvenient doses and treatment schedules. LASSBio-1736 was des...

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Detalles Bibliográficos
Autores principales: de Queiroz, Aline Cavalcanti, Barbosa, Gisele, de Oliveira, Victória Regina Thomaz, de Mattos Alves, Hélio, Alves, Marina Amaral, Carregaro, Vanessa, Santana da Silva, João, Barreiro, Eliezer Jesus, Alexandre-Moreira, Magna Suzana, Lima, Lidia Moreira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9170106/
https://www.ncbi.nlm.nih.gov/pubmed/35666748
http://dx.doi.org/10.1371/journal.pone.0269447