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Pre-clinical evaluation of LASSBio-1491: From in vitro pharmacokinetic study to in vivo leishmanicidal activity
Leishmaniasis is a public health issue. It is among the top five parasitic illnesses worldwide and is one of the most neglected diseases. The current treatment disease includes limitations of toxicity, variable efficacy, high costs and inconvenient doses and treatment schedules. LASSBio-1736 was des...
Autores principales: | de Queiroz, Aline Cavalcanti, Barbosa, Gisele, de Oliveira, Victória Regina Thomaz, de Mattos Alves, Hélio, Alves, Marina Amaral, Carregaro, Vanessa, Santana da Silva, João, Barreiro, Eliezer Jesus, Alexandre-Moreira, Magna Suzana, Lima, Lidia Moreira |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9170106/ https://www.ncbi.nlm.nih.gov/pubmed/35666748 http://dx.doi.org/10.1371/journal.pone.0269447 |
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