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Needleless administration of advanced therapies into the skin via the appendages using a hypobaric patch

Advanced therapies are commonly administered via injection even when they act within the skin tissue, and this increases the chances of off-target effects. Here we report the use of a skin patch containing a hypobaric chamber that induces skin dome formation to enable needleless delivery of advanced...

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Detalles Bibliográficos
Autores principales: Benaouda, Faiza, Inacio, Ricardo, Lim, Chui Hua, Park, Haeeun, Pitcher, Thomas, Alhnan, Mohamed A., Aly, Mazen M. S., Al-Jamal, Khuloud T, Chan, Ka-lung, Gala, Rikhav P., Sebastia-Saez, Daniel, Cui, Liang, Chen, Tao, Keeble, Julie, Jones, Stuart A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9170139/
https://www.ncbi.nlm.nih.gov/pubmed/35482922
http://dx.doi.org/10.1073/pnas.2120340119