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Needleless administration of advanced therapies into the skin via the appendages using a hypobaric patch
Advanced therapies are commonly administered via injection even when they act within the skin tissue, and this increases the chances of off-target effects. Here we report the use of a skin patch containing a hypobaric chamber that induces skin dome formation to enable needleless delivery of advanced...
Autores principales: | Benaouda, Faiza, Inacio, Ricardo, Lim, Chui Hua, Park, Haeeun, Pitcher, Thomas, Alhnan, Mohamed A., Aly, Mazen M. S., Al-Jamal, Khuloud T, Chan, Ka-lung, Gala, Rikhav P., Sebastia-Saez, Daniel, Cui, Liang, Chen, Tao, Keeble, Julie, Jones, Stuart A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9170139/ https://www.ncbi.nlm.nih.gov/pubmed/35482922 http://dx.doi.org/10.1073/pnas.2120340119 |
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