Systems biology approach to functionally assess the Clostridioides difficile pangenome reveals genetic diversity with discriminatory power

Combatting Clostridioides difficile infections, a dominant cause of hospital-associated infections with incidence and resulting deaths increasing worldwide, is complicated by the frequent emergence of new virulent strains. Here, we employ whole-genome sequencing, high-throughput phenotypic screening...

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Detalles Bibliográficos
Autores principales: Norsigian, Charles J., Danhof, Heather A., Brand, Colleen K., Midani, Firas S., Broddrick, Jared T., Savidge, Tor C., Britton, Robert A., Palsson, Bernhard O., Spinler, Jennifer K., Monk, Jonathan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9170149/
https://www.ncbi.nlm.nih.gov/pubmed/35476524
http://dx.doi.org/10.1073/pnas.2119396119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9170149/
https://www.ncbi.nlm.nih.gov/pubmed/35476524
http://dx.doi.org/10.1073/pnas.2119396119

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