Dromedary camel nanobodies broadly neutralize SARS-CoV-2 variants

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike is a trimer of S1/S2 heterodimers with three receptor-binding domains (RBDs) at the S1 subunit for human angiotensin-converting enzyme 2 (hACE2). Due to their small size, nanobodies can recognize protein cavities that are not acc...

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Detalles Bibliográficos
Autores principales: Hong, Jessica, Kwon, Hyung Joon, Cachau, Raul, Chen, Catherine Z., Butay, Kevin John, Duan, Zhijian, Li, Dan, Ren, Hua, Liang, Tianyuzhou, Zhu, Jianghai, Dandey, Venkata P., Martin, Negin P., Esposito, Dominic, Ortega-Rodriguez, Uriel, Xu, Miao, Borgnia, Mario J., Xie, Hang, Ho, Mitchell
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9170159/
https://www.ncbi.nlm.nih.gov/pubmed/35476528
http://dx.doi.org/10.1073/pnas.2201433119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9170159/
https://www.ncbi.nlm.nih.gov/pubmed/35476528
http://dx.doi.org/10.1073/pnas.2201433119

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