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Dromedary camel nanobodies broadly neutralize SARS-CoV-2 variants

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike is a trimer of S1/S2 heterodimers with three receptor-binding domains (RBDs) at the S1 subunit for human angiotensin-converting enzyme 2 (hACE2). Due to their small size, nanobodies can recognize protein cavities that are not acc...

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Detalles Bibliográficos
Autores principales:	Hong, Jessica, Kwon, Hyung Joon, Cachau, Raul, Chen, Catherine Z., Butay, Kevin John, Duan, Zhijian, Li, Dan, Ren, Hua, Liang, Tianyuzhou, Zhu, Jianghai, Dandey, Venkata P., Martin, Negin P., Esposito, Dominic, Ortega-Rodriguez, Uriel, Xu, Miao, Borgnia, Mario J., Xie, Hang, Ho, Mitchell
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2022
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9170159/ https://www.ncbi.nlm.nih.gov/pubmed/35476528 http://dx.doi.org/10.1073/pnas.2201433119

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