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A unique bacterial secretion machinery with multiple secretion centers

The Porphyromonas gingivalis type IX secretion system (T9SS) promotes periodontal disease by secreting gingipains and other virulence factors. By in situ cryoelectron tomography, we report that the P. gingivalis T9SS consists of 18 PorM dimers arranged as a large, caged ring in the periplasm. Near t...

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Detalles Bibliográficos
Autores principales: Song, Liqiang, Perpich, John D., Wu, Chenggang, Doan, Thierry, Nowakowska, Zuzanna, Potempa, Jan, Christie, Peter J., Cascales, Eric, Lamont, Richard J., Hu, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9170169/
https://www.ncbi.nlm.nih.gov/pubmed/35471908
http://dx.doi.org/10.1073/pnas.2119907119