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A unique bacterial secretion machinery with multiple secretion centers
The Porphyromonas gingivalis type IX secretion system (T9SS) promotes periodontal disease by secreting gingipains and other virulence factors. By in situ cryoelectron tomography, we report that the P. gingivalis T9SS consists of 18 PorM dimers arranged as a large, caged ring in the periplasm. Near t...
Autores principales: | Song, Liqiang, Perpich, John D., Wu, Chenggang, Doan, Thierry, Nowakowska, Zuzanna, Potempa, Jan, Christie, Peter J., Cascales, Eric, Lamont, Richard J., Hu, Bo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9170169/ https://www.ncbi.nlm.nih.gov/pubmed/35471908 http://dx.doi.org/10.1073/pnas.2119907119 |
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