Allele-specific collateral and fitness effects determine the dynamics of fluoroquinolone resistance evolution

Collateral sensitivity (CS), which arises when resistance to one antibiotic increases sensitivity toward other antibiotics, offers treatment opportunities to constrain or reverse the evolution of antibiotic resistance. The applicability of CS-informed treatments remains uncertain, in part because we...

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Detalles Bibliográficos
Autores principales: Liakopoulos, Apostolos, Aulin, Linda B. S., Buffoni, Matteo, Fragkiskou, Efthymia, Coen van Hasselt, J. G., Rozen, Daniel E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9170170/
https://www.ncbi.nlm.nih.gov/pubmed/35476512
http://dx.doi.org/10.1073/pnas.2121768119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9170170/
https://www.ncbi.nlm.nih.gov/pubmed/35476512
http://dx.doi.org/10.1073/pnas.2121768119

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