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Mitochondrial mutations alter endurance exercise response and determinants in mice

Primary mitochondrial diseases (PMDs) are a heterogeneous group of metabolic disorders that can be caused by hundreds of mutations in both mitochondrial DNA (mtDNA) and nuclear DNA (nDNA) genes. Current therapeutic approaches are limited, although one approach has been exercise training. Endurance e...

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Detalles Bibliográficos
Autores principales: Schaefer, Patrick M., Rathi, Komal, Butic, Arrienne, Tan, Wendy, Mitchell, Katherine, Wallace, Douglas C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9170171/
https://www.ncbi.nlm.nih.gov/pubmed/35482926
http://dx.doi.org/10.1073/pnas.2200549119