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Epithelial-derived exosomes promote M2 macrophage polarization via Notch2/SOCS1 during mechanical ventilation

Alveolar macrophages (AMs) play an essential role in ventilator-induced lung injury (VILI). Exosomes and their cargo, including microRNAs (miRNAs/miRs) serve as regulators of the intercellular communications between macrophages and epithelial cells (ECs), and are involved in maintaining homeostasis...

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Detalles Bibliográficos
Autores principales: Wang, Yanting, Xie, Wanli, Feng, Yiqi, Xu, Zhenzhen, He, Yuyao, Xiong, Yue, Chen, Lu, Li, Xia, Liu, Jie, Liu, Guoyang, Wu, Qingping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9170191/
https://www.ncbi.nlm.nih.gov/pubmed/35616134
http://dx.doi.org/10.3892/ijmm.2022.5152