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Genome editing in the unicellular holozoan Capsaspora owczarzaki suggests a premetazoan role for the Hippo pathway in multicellular morphogenesis

Animal development is mediated by a surprisingly small set of canonical signaling pathways such as Wnt, Hedgehog, TGF-beta, Notch, and Hippo pathways. Although once thought to be present only in animals, recent genome sequencing has revealed components of these pathways in the closest unicellular re...

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Detalles Bibliográficos
Autores principales: Phillips, Jonathan E, Santos, Maribel, Konchwala, Mohammed, Xing, Chao, Pan, Duojia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9170242/
https://www.ncbi.nlm.nih.gov/pubmed/35659869
http://dx.doi.org/10.7554/eLife.77598