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Transposon mutagenesis in Mycobacterium abscessus identifies an essential penicillin-binding protein involved in septal peptidoglycan synthesis and antibiotic sensitivity

Mycobacterium abscessus (Mab) is a rapidly growing non-tuberculous mycobacterium (NTM) that causes a wide range of infections. Treatment of Mab infections is difficult because the bacterium is intrinsically resistant to many classes of antibiotics. Developing new and effective treatments against Mab...

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Detalles Bibliográficos
Autores principales: Akusobi, Chidiebere, Benghomari, Bouchra S, Zhu, Junhao, Wolf, Ian D, Singhvi, Shreya, Dulberger, Charles L, Ioerger, Thomas R, Rubin, Eric J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9170245/
https://www.ncbi.nlm.nih.gov/pubmed/35659317
http://dx.doi.org/10.7554/eLife.71947