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Strength of interactions in the Notch gene regulatory network determines patterning and fate in the notochord

Development of multicellular organisms requires the generation of gene expression patterns that determines cell fate and organ shape. Groups of genetic interactions known as Gene Regulatory Networks (GRNs) play a key role in the generation of such patterns. However, how the topology and parameters o...

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Detalles Bibliográficos
Autores principales: Sánchez-Iranzo, Héctor, Halavatyi, Aliaksandr, Diz-Muñoz, Alba
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9170247/
https://www.ncbi.nlm.nih.gov/pubmed/35658971
http://dx.doi.org/10.7554/eLife.75429