Microbiota and adipocyte mitochondrial damage in type 2 diabetes are linked by Mmp12(+) macrophages

Microbiota contribute to the induction of type 2 diabetes by high-fat/high-sugar (HFHS) diet, but which organs/pathways are impacted by microbiota remain unknown. Using multiorgan network and transkingdom analyses, we found that microbiota-dependent impairment of OXPHOS/mitochondria in white adipose...

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Detalles Bibliográficos
Autores principales: Li, Zhipeng, Gurung, Manoj, Rodrigues, Richard R., Padiadpu, Jyothi, Newman, Nolan K., Manes, Nathan P., Pederson, Jacob W., Greer, Renee L., Vasquez-Perez, Stephany, You, Hyekyoung, Hioki, Kaito A., Moulton, Zoe, Fel, Anna, De Nardo, Dominic, Dzutsev, Amiran K., Nita-Lazar, Aleksandra, Trinchieri, Giorgio, Shulzhenko, Natalia, Morgun, Andrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9170383/
https://www.ncbi.nlm.nih.gov/pubmed/35657352
http://dx.doi.org/10.1084/jem.20220017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9170383/
https://www.ncbi.nlm.nih.gov/pubmed/35657352
http://dx.doi.org/10.1084/jem.20220017

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