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Depression and stress levels increase risk of liver cancer through epigenetic downregulation of hypocretin

Recent studies suggest that Hypocretin (HCRT, Orexin) are involved in stress regulation of depression through the hypothalamic-pituitary-adrenal (HPA) axis. However, the molecular mechanism by which Hypocretin regulate neurobiological responses is unknown. Herein, the effects of chronic stress on th...

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Detalles Bibliográficos
Autores principales: Pu, Chunyun, Tian, Shaorong, He, Sanxiu, Chen, Weihong, He, Yuanyuan, Ren, Hongyan, Zhu, Jing, Tang, Jun, Huang, Xiaolan, Xiang, Ying, Fu, Yixiao, Xiang, Tingxiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9170575/
https://www.ncbi.nlm.nih.gov/pubmed/35685472
http://dx.doi.org/10.1016/j.gendis.2020.11.013