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AAV6 as an effective gene delivery vector for prolonged transgene expression in intervertebral disc cells in vivo

Intervertebral disc degeneration is the main contributor to low back pain, now the leading cause of disability worldwide. Gene transfer, either in a therapeutic attempt or in basic research to understand the mechanisms of disc degeneration, is a fascinating and promising tool to manipulate the compl...

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Detalles Bibliográficos
Autores principales: Kim, Chi Heon, Oliver, Colleen, Dar, Hamid, Drissi, Hicham, Presciutti, Steven M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9170577/
https://www.ncbi.nlm.nih.gov/pubmed/35685478
http://dx.doi.org/10.1016/j.gendis.2020.12.009