ADSC-Exosomes Alleviate MTX-induced Rat Neuronal Damage by Activating Nrf2-ARE Pathway

The aim of this study was to analyze the efficacy and underlying mechanism of adipose-derived mesenchymal stem cell exosome (ADSC-exosomes)–mediated protection on methotrexate (MTX)–induced neuronal damage. We established a H(2)O(2)­induced oxidative stress model in vitro, as well as an MTX-induced...

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Detalles Bibliográficos
Autores principales: Huang, Tingting, Tong, Hongfei, Zhou, Haixia, Wang, Juxiang, Hu, Linglong, Wang, Yao, Huang, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9170627/
https://www.ncbi.nlm.nih.gov/pubmed/35322376
http://dx.doi.org/10.1007/s12031-022-01996-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9170627/
https://www.ncbi.nlm.nih.gov/pubmed/35322376
http://dx.doi.org/10.1007/s12031-022-01996-x

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