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Altered DNA methylation at age-associated CpG sites in children with growth disorders: impact on age estimation?

Age estimation based on DNA methylation (DNAm) can be applied to children, adolescents and adults, but many CG dinucleotides (CpGs) exhibit different kinetics of age-associated DNAm across these age ranges. Furthermore, it is still unclear how growth disorders impact epigenetic age predictions, and...

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Detalles Bibliográficos
Autores principales: Mayer, F., Becker, J., Reinauer, C., Böhme, P., Eickhoff, S. B., Koop, B., Gündüz, T., Blum, J., Wagner, W., Ritz-Timme, S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9170667/
https://www.ncbi.nlm.nih.gov/pubmed/35551445
http://dx.doi.org/10.1007/s00414-022-02826-w