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Histological and Top-Down Proteomic Analyses of the Visual Pathway in the Cuprizone Demyelination Model

A change in visual perception is a frequent early symptom of multiple sclerosis (MS), the pathoaetiology of which remains unclear. Following a slow demyelination process caused by 12 weeks of low-dose (0.1%) cuprizone (CPZ) consumption, histology and proteomics were used to investigate components of...

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Detalles Bibliográficos
Autores principales: Almuslehi, Mohammed S. M., Sen, Monokesh K., Shortland, Peter J., Mahns, David A., Coorssen, Jens R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9170674/
https://www.ncbi.nlm.nih.gov/pubmed/35644788
http://dx.doi.org/10.1007/s12031-022-01997-w