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Integrative epigenomic and transcriptomic analysis reveals the requirement of JUNB for hematopoietic fate induction
Human pluripotent stem cell differentiation towards hematopoietic progenitor cell can serve as an in vitro model for human embryonic hematopoiesis, but the dynamic change of epigenome and transcriptome remains elusive. Here, we systematically profile the chromatin accessibility, H3K4me3 and H3K27me3...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9170695/ https://www.ncbi.nlm.nih.gov/pubmed/35668082 http://dx.doi.org/10.1038/s41467-022-30789-4 |