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Integrative epigenomic and transcriptomic analysis reveals the requirement of JUNB for hematopoietic fate induction

Human pluripotent stem cell differentiation towards hematopoietic progenitor cell can serve as an in vitro model for human embryonic hematopoiesis, but the dynamic change of epigenome and transcriptome remains elusive. Here, we systematically profile the chromatin accessibility, H3K4me3 and H3K27me3...

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Detalles Bibliográficos
Autores principales: Chen, Xia, Wang, Peiliang, Qiu, Hui, Zhu, Yonglin, Zhang, Xingwu, Zhang, Yaxuan, Duan, Fuyu, Ding, Shuangyuan, Guo, Jianying, Huang, Yue, Na, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9170695/
https://www.ncbi.nlm.nih.gov/pubmed/35668082
http://dx.doi.org/10.1038/s41467-022-30789-4