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Estrogen receptor positive breast cancers have patient specific hormone sensitivities and rely on progesterone receptor

Estrogen and progesterone receptor (ER, PR) signaling control breast development and impinge on breast carcinogenesis. ER is an established driver of ER + disease but the role of the PR, itself an ER target gene, is debated. We assess the issue in clinically relevant settings by a genetic approach a...

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Detalles Bibliográficos
Autores principales: Scabia, Valentina, Ayyanan, Ayyakkannu, De Martino, Fabio, Agnoletto, Andrea, Battista, Laura, Laszlo, Csaba, Treboux, Assia, Zaman, Khalil, Stravodimou, Athina, Jallut, Didier, Fiche, Maryse, Bucher, Philip, Ambrosini, Giovanna, Sflomos, George, Brisken, Cathrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9170711/
https://www.ncbi.nlm.nih.gov/pubmed/35668111
http://dx.doi.org/10.1038/s41467-022-30898-0