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Syntaxin 18 regulates the DNA damage response and epithelial-to-mesenchymal transition to promote radiation resistance of lung cancer

Radiotherapy is an important modality in lung cancer treatment. Despite advances in treatment planning and dose delivery, patient benefit is still limited by in-field relapse and metastatic recurrence. Simultaneous application of cisplatinum-based chemotherapy leads to moderately improved outcomes,...

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Detalles Bibliográficos
Autores principales: Thumser-Henner, Clotilde, Oeck, Sebastian, Kalmbach, Sophie, Forster, Jan, Kindl, Franziska, Sak, Ali, Schramm, Alexander, Schuler, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9170725/
https://www.ncbi.nlm.nih.gov/pubmed/35668077
http://dx.doi.org/10.1038/s41419-022-04978-4