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Mitochondrial reactive oxygen is critical for IL-12/IL-18-induced IFN-γ production by CD4(+) T cells and is regulated by Fas/FasL signaling
Mitochondrial activation and the production of mitochondrial reactive oxygen species (mROS) are crucial for CD4(+) T cell responses and have a role in naïve cell signaling after TCR activation. However, little is known about mROS role in TCR-independent signaling and in recall responses. Here, we fo...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9170726/ https://www.ncbi.nlm.nih.gov/pubmed/35668079 http://dx.doi.org/10.1038/s41419-022-04907-5 |