Mitochondrial reactive oxygen is critical for IL-12/IL-18-induced IFN-γ production by CD4(+) T cells and is regulated by Fas/FasL signaling

Mitochondrial activation and the production of mitochondrial reactive oxygen species (mROS) are crucial for CD4(+) T cell responses and have a role in naïve cell signaling after TCR activation. However, little is known about mROS role in TCR-independent signaling and in recall responses. Here, we fo...

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Detalles Bibliográficos
Autores principales: Rackov, Gorjana, Tavakoli Zaniani, Parinaz, Colomo del Pino, Sara, Shokri, Rahman, Monserrat, Jorge, Alvarez-Mon, Melchor, Martinez-A, Carlos, Balomenos, Dimitrios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9170726/
https://www.ncbi.nlm.nih.gov/pubmed/35668079
http://dx.doi.org/10.1038/s41419-022-04907-5

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