Sirt6-mediated epigenetic modification of DNA accessibility is essential for Pou2f3-induced thymic tuft cell development

Thymic epithelial cells (TECs) are essential for the production of self-tolerant T cells. The newly identified thymic tuft cells are regulated by Pou2f3 and represent important elements for host type 2 immunity. However, epigenetic involvement in thymic tuft cell development remains unclear. We perf...

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Detalles Bibliográficos
Autores principales: Zhang, Qian, Zhang, Jiayu, Lei, Tong, Liang, Zhanfeng, Dong, Xue, Sun, Liguang, Zhao, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9170729/
https://www.ncbi.nlm.nih.gov/pubmed/35668088
http://dx.doi.org/10.1038/s42003-022-03484-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9170729/
https://www.ncbi.nlm.nih.gov/pubmed/35668088
http://dx.doi.org/10.1038/s42003-022-03484-9

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