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Oleic Acid and Eicosapentaenoic Acid Reverse Palmitic Acid-induced Insulin Resistance in Human HepG2 Cells via the Reactive Oxygen Species/JUN Pathway

Oleic acid (OA), a monounsaturated fatty acid (MUFA), has previously been shown to reverse saturated fatty acid palmitic acid (PA)-induced hepatic insulin resistance (IR). However, its underlying molecular mechanism is unclear. In addition, previous studies have shown that eicosapentaenoic acid (EPA...

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Detalles Bibliográficos
Autores principales: Sun, Yaping, Wang, Jifeng, Guo, Xiaojing, Zhu, Nali, Niu, Lili, Ding, Xiang, Xie, Zhensheng, Chen, Xiulan, Yang, Fuquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9170756/
https://www.ncbi.nlm.nih.gov/pubmed/33631425
http://dx.doi.org/10.1016/j.gpb.2019.06.005