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SGPL1 stimulates VPS39 recruitment to the mitochondria in MICU1 deficient cells

OBJECTIVE: Mitochondrial “retrograde” signaling may stimulate organelle biogenesis as a compensatory adaptation to aberrant activity of the oxidative phosphorylation (OXPHOS) system. To maintain energy-consuming processes in OXPHOS deficient cells, alternative metabolic pathways are functionally cou...

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Detalles Bibliográficos
Autores principales: Jackson, Joshua, Wischhof, Lena, Scifo, Enzo, Pellizzer, Anna, Wang, Yiru, Piazzesi, Antonia, Gentile, Debora, Siddig, Sana, Stork, Miriam, Hopkins, Chris E., Händler, Kristian, Weis, Joachim, Roos, Andreas, Schultze, Joachim L., Nicotera, Pierluigi, Ehninger, Dan, Bano, Daniele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9170783/
https://www.ncbi.nlm.nih.gov/pubmed/35452878
http://dx.doi.org/10.1016/j.molmet.2022.101503