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Single‐nucleus transcriptome analysis reveals disease‐ and regeneration‐associated endothelial cells in white matter vascular dementia

BACKGROUND: Vascular dementia (VaD) is the accumulation of vascular lesions in the subcortical white matter of the brain. These lesions progress and there is no direct medical therapy. AIMS: To determine the specific cellular responses in VaD so as to provide molecular targets for therapeutic develo...

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Detalles Bibliográficos
Autores principales: Mitroi, Daniel N., Tian, Min, Kawaguchi, Riki, Lowry, William E., Carmichael, S. Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9170821/
https://www.ncbi.nlm.nih.gov/pubmed/35543222
http://dx.doi.org/10.1111/jcmm.17315