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Paeonol Interferes With Quorum-Sensing in Pseudomonas aeruginosa and Modulates Inflammatory Responses In Vitro and In Vivo

Developing quorum-sensing (QS) based anti-infection drugs is one of the most powerful strategies to combat multidrug-resistant bacteria. Paeonol has been proven to attenuate the QS-controlled virulence factors of P. aeruginosa by down-regulating the transcription of QS signal molecules. This researc...

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Detalles Bibliográficos
Autores principales: Tang, Huaqiao, Yang, Dan, Zhu, Ling, Shi, Fei, Ye, Gang, Guo, Hongrui, Deng, Huidan, Zhao, Ling, Xu, Zhiwen, Li, Yinglun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9170885/
https://www.ncbi.nlm.nih.gov/pubmed/35686124
http://dx.doi.org/10.3389/fimmu.2022.896874