Effects of Ultramicronized Palmitoylethanolamide on Mitochondrial Bioenergetics, Cerebral Metabolism, and Glutamatergic Transmission: An Integrated Approach in a Triple Transgenic Mouse Model of Alzheimer's Disease

The therapeutic potential of ultramicronized palmitoylethanolamide (um-PEA) was investigated in young (6-month-old) and adult (12-month-old) 3 × Tg-AD mice, which received um-PEA for 3 months via a subcutaneous delivery system. Mitochondrial bioenergetics, ATP homeostasis, and magnetic resonance ima...

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Detalles Bibliográficos
Autores principales: Bellanti, Francesco, Bukke, Vidyasagar Naik, Moola, Archana, Villani, Rosanna, Scuderi, Caterina, Steardo, Luca, Palombelli, Gianmauro, Canese, Rossella, Beggiato, Sarah, Altamura, Mario, Vendemiale, Gianluigi, Serviddio, Gaetano, Cassano, Tommaso
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Aging Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9170916/
https://www.ncbi.nlm.nih.gov/pubmed/35686025
http://dx.doi.org/10.3389/fnagi.2022.890855

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9170916/
https://www.ncbi.nlm.nih.gov/pubmed/35686025
http://dx.doi.org/10.3389/fnagi.2022.890855

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