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Effects of Ultramicronized Palmitoylethanolamide on Mitochondrial Bioenergetics, Cerebral Metabolism, and Glutamatergic Transmission: An Integrated Approach in a Triple Transgenic Mouse Model of Alzheimer's Disease
The therapeutic potential of ultramicronized palmitoylethanolamide (um-PEA) was investigated in young (6-month-old) and adult (12-month-old) 3 × Tg-AD mice, which received um-PEA for 3 months via a subcutaneous delivery system. Mitochondrial bioenergetics, ATP homeostasis, and magnetic resonance ima...
Autores principales: | Bellanti, Francesco, Bukke, Vidyasagar Naik, Moola, Archana, Villani, Rosanna, Scuderi, Caterina, Steardo, Luca, Palombelli, Gianmauro, Canese, Rossella, Beggiato, Sarah, Altamura, Mario, Vendemiale, Gianluigi, Serviddio, Gaetano, Cassano, Tommaso |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9170916/ https://www.ncbi.nlm.nih.gov/pubmed/35686025 http://dx.doi.org/10.3389/fnagi.2022.890855 |
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