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Melatonin Improved the Survival of Multi-Territory Perforator Flaps by Promoting Angiogenesis and Inhibiting Apoptosis via the NRF2/FUNDC1 Axis

Background: Multi-territory perforator flaps are a reconstructive measure for repairing large soft tissue defects caused by tumors or trauma. However, the use of these flaps in clinical practice has been restricted due to the uncertain blood supply. Therefore, promoting the survival of the multi-ter...

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Detalles Bibliográficos
Autores principales: Huang, Chengxiong, Qing, Liming, Pang, Xiaoyang, Fu, Jinfei, Xiao, Yu, Tang, Juyu, Wu, Panfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9170937/
https://www.ncbi.nlm.nih.gov/pubmed/35685624
http://dx.doi.org/10.3389/fphar.2022.921189